In-Vitro Toxicology/ Toxicity Testing Market by Industry (Diagnostic, Pharmaceutical, Cosmetics, Chemical), Technology (Cell Culture, HTS, Omics), Applications (Systemic, Dermal, Ocular), Method (Cellular Assay, Ex vivo, In Silico) - Global Forecast to 2018

世界の生体外毒性/毒性テスト市場動向及び予測(~2018)

◆タイトル:In-Vitro Toxicology/ Toxicity Testing Market by Industry (Diagnostic, Pharmaceutical, Cosmetics, Chemical), Technology (Cell Culture, HTS, Omics), Applications (Systemic, Dermal, Ocular), Method (Cellular Assay, Ex vivo, In Silico) - Global Forecast to 2018
◆商品コード:BT 2373
◆調査・発行会社:MarketsandMarkets
◆発行日:2014年4月
◆ページ数:246
◆レポート形式:PDF / 英語
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◆調査対象地域:グローバル
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【レポートの概要】

本調査レポートでは、"世界の生体外毒性/毒性テスト市場動向及び予測(~2018)"について調査・分析し、イントロダクション、エグゼクティブサマリー、プレミアムインサイト、市場概観、市場の動態、技術別分析、用途別分析、地域別分析、市場規模及び予測、競争状況、新製品発売、主要企業(ベンダー)分析等の情報をお届けいたします。

Attributed to the support offered by the European government, the in vitro toxicology testing market in Europe was the largest in 2013 and is expected to hold the same stance by 2018
There has been a substantial rise in the costs to develop a new pharmaceutical product in recent years. This is specially observed when a new compound enters animal testing and clinical trials. The use of animals in experimentation is becoming dearer, primarily due to the costs involved in breeding and acquisition of animals, due to the complexity of procedures involved in the in vivo testing, and several other ethical issues including concerns for animal welfare. Moreover the rates of drug attrition have also risen in recent years due to lesser availability of data on the toxicity profiles of the candidates that are under development process. To counteract these issues there has been a rise in the development of in vitro methods that are alternative to animal testing. A paradigm shift is observed towards emerging technologies such as assays based on human cells or non-mammalian models, high throughput testing, omics approaches, ex vivo models, and in silico techniques.
Pharmaceutical industry was the largest segment in the in vitro toxicology testing market which is expected to hold the leading position in the coming five years. This is largely attributed to the widely recognized factors of evaluation of the toxicity levels in the early stages of development that necessitates the use of in vitro methods to improve the drug toxicity profiles. On the other hand, cosmetic industry will be the fastest growing industry in the coming years as a result of the huge government support in Europe to ban the use of animals for testing the toxic effects of beauty products. The European government has also forbidden the marketing of those cosmetics product which were tested on animals.
For better interpretation of in vitro results cell culture technology involving cell based assays has emerged as a momentous technology that has been driving the in vitro toxicology testing market. With the advancement in the cell culture technology a number of cell models are emerging that provide insights into the biochemical and signaling process that better interprets the in vitro data. With the increasing demand of emergent 3D models the cell culture technology is estimated to be the fastest growing technology in the next five years.
With the implementation of several laws through adoption of various initiatives by the European government to stop animal testing; the European region is the leading market. The government promotes the use of in vitro techniques through launch of programs such as AXLR8 for the purpose of monitoring EU funded 3Rs research activities with the aim of accelerating the transition from in vivo testing to in vitro testing. The emerging countries in Asia such as China and India will register high growth in the coming years, this can be attributed to the low development costs offered by these nations. Moreover due to the economic growth of these nations there has been a rise in the investments in these countries which is further propelling the market in a positive direction.
The grey area while estimating the market size was the overlapping nature of the applications while segregating them based on evaluation of endpoints involved. These included testing of end points such as acute systemic toxicity, pharmacokinetics & metabolism, repeated dose/organ toxicity under systemic toxicity, dermal penetration, skin irritation/corrosion and skin sensitization under dermal toxicity. This was later clarified with the help of various experts that participated during the study.
From an insight perspective, this research report focuses on the qualitative data, market size, share, growth of various segments and sub-segments, competitive landscape, and company profiles. The qualitative data covers various levels of industry analysis such as market dynamics (drivers, restraints, opportunities, and threats). The report also offers market shares, sizes, and related growth of various segments in the industry. It also focuses on the emerging and high-growth segments of in vitro toxicology testing market, high-growth regions, and the initiatives of respective governments.
The competitive landscape covers the growth strategies adopted by industry players in the last three years. The company profiles comprise the basic views on the key players in the in-vitro toxicology testing market, product portfolios, developments, and strategies adopted by market players to maintain and increase their market shares in the near future. The above mentioned market research data, current market size, and forecast of future trends will help the key players and new entrants to make the necessary decisions regarding product offerings, geographic focus, change in approach, R&D investments for innovations in products and technologies, and levels of output in order to remain successful.

【レポートの目次】

Table Of Contents

1 Introduction (Page No. – 21)
1.1 Objectives Of The Study
1.2 Report Description
1.3 Markets Covered
1.4 Stakeholders
1.5 Market Scope
1.6 Research Methodology
1.6.1 Market Size Estimation & Data Triangulation
1.6.2 Key Data Points From Secondary Sources
1.6.3 Key Data Points From Primary Sources
1.6.4 Assumptions

2 Executive Summary (Page No. – 34)

3 Premium Insights (Page No. – 40)
3.1 Market Size
3.2 Market Dynamics
3.3 In-Vitro Toxicity Testing Market Size Snapshot
3.4 In-Vitro Toxicity Testing, Geographic Analysis By Industry
3.5 In-Vitro Toxicity Testing Market Size, By Technology
3.6 In-Vitro Toxicity Testing Market Size, By Method
3.7 In-Vitro Toxicity Testing Market, By Application

4 Market Overview (Page No. – 47)
4.1 Introduction
4.2 Market Segmentation
4.3 Market Dynamics
4.3.1 Drivers
4.3.1.1 Dearth Of Publicly Accessible Databases to Facilitate The Use Of In Vitro Test Methods
4.3.1.2 New and Promising Technologies to Propel Market
4.3.1.3 Technological Advancements and Shifting Focus to Innovative Approaches Of 3d Cell Cultures Are Driving The Cell Culture Technology Market
4.3.1.4 Opposition to Animal Testing Will Help Shift The Focus to In Vitro Testing
4.3.2 Restraints
4.3.2.1 Technological Disadvantages Associated With In Vitro Tests Limit Their Use
4.3.2.2 In Vitro Models Cannot Detect Autoimmunity and Immunostimulation
4.3.2.3 Predictive Ability Of In Vitro Testing Leads to Decreasing Adoption Of These Tests
4.3.3 Opportunities
4.3.3.1 The Toxicology In The 21st Century (Tox21) Program
4.3.3.2 Increasing Drug Discovery and Innovation and Modernization in The Market
4.3.3.3 Growing Demand For In Vitro Toxicology in The European Market
4.3.4 Threats
4.3.4.1 Reluctance Of Regulatory Authorities to Consider Alternate Methods For Proving Safety and Efficacy
4.4 Burning Issues
4.4.1 Validation Of New In Vitro Methods
4.4.2 Differences in Opinion Between The U.S. and Eu Regulatory Authorities
4.5 Winning Imperatives
4.5.1 3d Human Hepatocyte Models to Boost The In Vitro Testing Market

5 By Industry (Page No. – 60)
5.1 Introduction
5.2 Diagnostics
5.2.1 Diagnostics, By Type
5.2.1.1 Forensics
5.2.1.2 Drug Abuse & Workplace Drug Testing
5.2.2 Diagnostics, By Sample
5.2.2.1 Urine Screening
5.2.2.2 Alcohol Screening
5.2.2.3 Oral Fluid Screening
5.2.2.4 Hair Screening
5.2.2.5 Others
5.3 Cosmetics & Household Products
5.4 Pharmaceutical Industry
5.5 Chemicals Industry
5.6 Food Industry

6 By Technology (Page No. – 86)
6.1 Introduction
6.1.1 Cell Culture Technology
6.1.1.1 Primary Monolayer and Three-Dimensional Cell Cultures
6.1.2 High Throughput Technologies
6.1.2.1 High Throughput Toxicity Testing
6.1.2.2 The Epa Toxcast Program
6.1.3 Molecular Imaging Technologies
6.1.3.1 Molecular Imaging Technologies
6.1.3.2 High Content Imaging Technologies
6.1.4 Omics Technologies
6.1.4.1 Genomics
6.1.4.2 Toxicogenomics
6.1.4.3 Proteomics
6.1.4.4 Metabolomics

7 By Application (Page No. – 108)
7.1 Introduction
7.2 Systemic Toxicity
7.3 Dermal Toxicity
7.4 Ocular Toxicity
7.5 Endocrine Disruption (Reproductive/Developmental Toxicity)
7.6 Others (Admet, Organ-Specific Toxicity, Drug-Drug Interactions, Target/Pathway Assays, & Ecotoxicity)
7.6.1 Admet (Pharmacokinetics & Metabolism Testing)
7.6.2 Organ-Specific Toxicity
7.6.3 Drug-Drug Interactions
7.6.4 Target/Pathway Assays
7.6.5 Ecotoxicity

8 By Method (Page No. – 124)
8.1 Introduction
8.2 Cellular Assays
8.3 Biochemical Assays
8.4 In Silico Methods
8.5 Ex Vivo Models

9 Geographic Analysis (Page No. – 137)
9.1 Introduction
9.2 Europe
9.3 North America
9.4 Asia
9.5 Rest Of The World (ROW)

10 Competitive Landscape (Page No. – 168)
10.1 Introduction
10.2 Competitive Landscape, 2011-March 2014
10.3 New Product Launches
10.4 Mergers & Acquisitions
10.5 Agreements, Partnerships & Collaborations
10.6 Expansions
10.7 Other Developments

11 Company Profiles (Business Overview, Products & Services, Key Strategy, Recent Developments, Mnm View)* (Page No. – 191)
11.1 Agilent Technologies, Inc.
11.2 Alere, Inc.
11.3 Bio-Rad Laboratories, Inc.
11.4 Bioreliance, Inc. (A Subsidiary Of Sigma-Aldrich Corporation)
11.5 Catalent
11.6 Charles River Laboratories International, Inc.
11.7 Covance, Inc.
11.8 Cyprotex
11.9 Eurofins Scientific
11.1 GE Healthcare
11.11 Life Technologies Corporation (Thermo Fisher Scientific)
11.12 Quest Diagnostics

*Details On Products & Services, Key Strategy, & Recent Developments Might Not Be Captured in Case Of Unlisted Companies.

List Of Tables (67 Tables)

Table 1 In-Vitro Toxicology/Toxicity Testing, By Geography, 2011-2013 ($Million)
Table 2 Global Market, By Industry, 2011–2018 ($Million)
Table 3 Global Market For Diagnostics Industry, By Type, 2011–2018 ($Million)
Table 4 In Vitro Toxicology Testing Market For Diagnostics Industry, By Geography, 2011–2018 ($Million)
Table 5 Market For Forensics, By Geography, 2011–2018 ($Million)
Table 6 Market For Drug Abuse & Workplace Drug Testing, By Geography, 2011–2018 ($Million)
Table 7 Market For Diagnostics Industry, By Sample, 2011–2018 ($Million)
Table 8 Urine Sample Testing Market, By Geography, 2011–2018 ($Million)
Table 9 Alcohol Sample Testing Market, By Geography, 2011–2018 ($Million)
Table 10 Oral Sample Testing Market, By Geography, 2011–2018 ($Million)
Table 11 Hair Sample Testing Market, By Geography, 2011–2018 ($Million)
Table 12 Others Sample Testing Market, By Geography, 2011–2018 ($Million)
Table 13 In Vitro Toxicology Testing Market For Cosmetics & Household Industry, By Geography, 2011–2018 ($Million)
Table 14 In Vitro Toxicology Testing Market For Pharmaceutical Industry, By Geography, 2011–2018 ($Million)
Table 15 In Vitro Toxicology Testing Market For Chemical Industry, By Geography, 2011–2018 ($Million)
Table 16 Market For Food Industry, By Geography, 2011–2018 ($Million)
Table 17 Global In Vitro Toxicology Testing Market, By Technology, 2011–2018 ($Million)
Table 18 Market For Cell Culture Technology, By Geography, 2011–2018 ($Million)
Table 19 Global Market For Cell Culture Technology, By Industry, 2011–2018 ($Million)
Table 20 In Vitro Toxicology Testing Market For High Throughput Technology, By Geography, 2011–2018 ($Million)
Table 21 Global Market For High Throughput Technology, By Industry, 2011–2018 ($Million)
Table 22 Market For Molecular Imaging Technology, By Geography, 2011–2018 ($Million)
Table 23 Global Market For Molecular Imaging Technology, By Industry, 2011–2018 ($Million)
Table 24 Market For Omics Technologies, By Geography, 2011–2018 ($Million)
Table 25 Global Market For Omics Technologies, By Industry, 2011–2018 ($Million)
Table 26 Global Market, By Application, 2011–2018 ($Million)
Table 27 In Vitro Toxicity Testing Market For Systemic Toxicology, By Geography, 2011–2018 ($Million)
Table 28 Market For Dermal Toxicology, By Geography, 2011–2018 ($Milllion)
Table 29 Market For Ocular Toxicology, By Geography, 2011–2018 ($Milllion)
Table 30 Market For Endocrine Disruption, By Geography, 2011–2018 ($Milllion)
Table 31 Market For Other Applications, By Geography, 2011–2018 ($Milllion)
Table 32 Market, By Method, 2011–2018 ($Million)
Table 33 Primary Cell Culture Advantages & Limitations
Table 34 In Vitro Toxicity Testing Market For Cellular Assays, By Geography, 2011–2018 ($Million)
Table 35 In Vitro Toxicity Testing Market For Biochemical Assays, By Geography, 2011–2018 ($Million)
Table 36 In Vitro Toxicity Testing Market For In Silico Methods, By Geography, 2011–2018 ($Million)
Table 37 In Vitro Toxicity Testing Market For Ex Vivo Methods, By Geography, 2011–2018 ($Million)
Table 38 In Vitro Toxicology Market, By Geography, 2011–2018 ($Million)
Table 39 Europe: Market, By Industry, 2011–2018 ($Million)
Table 40 Europe: Market For Diagnostics Industry, By Sample, 2011–2018 ($Million)
Table 41 Europe: Market For Diagnostics Industry, By Type, 2011–2018 ($Million)
Table 42 Europe: Market, By Technology, 2011–2018 ($Million)
Table 43 Europe: Market, By Method, 2011–2018 ($Million)
Table 44 Europe: Market, By Application, 2011–2018 ($Million)
Table 45 North America: Market, By Industry, 2011–2018 ($Million)
Table 46 North America: Market For Diagnostics Industry, By Sample, 2011–2018 ($Million)
Table 47 North America: In Vitro Toxicology Testing Market For Diagnostics Industry, By Type, 2011–2018 ($Million)
Table 48 North America: Market, By Technology, 2011–2018 ($Million)
Table 49 North America: Market, By Method, 2011–2018 ($Million)
Table 50 North America: Market, By Application, 2011–2018 ($Million)
Table 51 Asia: Market, By Industry, 2011–2018 ($Million)
Table 52 Asia: Market For Diagnostics Industry, By Sample, 2011–2018 ($Million)
Table 53 Asia: Market For Diagnostics Industry, By Type, 2011–2018 ($Million)
Table 54 Asia: Market, By Technology, 2011–2018 ($Million)
Table 55 Asia: Market, By Method, 2011–2018 ($Million)
Table 56 Asia: Market, By Application, 2011–2018 ($Million)
Table 57 ROW: Market, By Industry, 2011–2018 ($Million)
Table 58 ROW: Market For Diagnostics Industry, By Sample, 2011–2018 ($Million)
Table 59 ROW: Market For Diagnostics Industry, By Type, 2011–2018 ($Million)
Table 60 ROW: Market, By Technology, 2011–2018 ($Million)
Table 61 ROW: Market, By Method, 2011–2018 ($Million)
Table 62 ROW: Market, By Application, 2011–2018 ($Million)
Table 63 New Product Launches, 2011–2014
Table 64 Mergers & Acquisitions, 2011–2014
Table 65 Agreements, Partnerships, & Collaborations, 2011–2014
Table 66 Expansions, 2011–2014
Table 67 Other Developments, 2011–2014

List Of Figures (25 Figures)

Figure 1 Market Crackdown & Data Triangulation
Figure 2 Market Forecasting Model
Figure 3 In Vitro Toxicology Testing, By Industry, 2013 ($Million)
Figure 4 Global Market, By Technology, 2013 ($Million)
Figure 5 Market Size, ($Million)
Figure 6 Market Dynamics
Figure 7 Market Size Snapshot, 2013 ($Million)
Figure 8 Geographic Analysis, By Industry, 2013 ($Million)
Figure 9 Global Market Size, By Technology, 2013 ($Million)
Figure 10 Global Market Size, By Method, 2013 ($Million)
Figure 11 Opportunity Matrix: Global Market, By Application, 2013
Figure 12 Market Crackdown & Data Triangulation
Figure 13 Global Market, By Industry,2013 ($Million)
Figure 14 Global Market, By Technology, 2013 Vs 2018 ($Million)
Figure 15 Primary Cell Cultures Advantages & Disadvantages
Figure 16 High Throughput Technology Advantages & Disadvantages
Figure 17 Molecular Imaging Technologies Advantages & Disadvantages
Figure 18 High Content Imaging Technologies Advantages & Disadvantages
Figure 19 Genomics Advantages & Disadvantages
Figure 20 Proteomics Advantages & Disadvantages
Figure 21 Metabolomics Advantages & Disadvantages
Figure 22 Global Market, By Application, 2013 ($Million)
Figure 23 Opportunity Matrix: Global Market, By Method, 2013
Figure 24 In Vitro Toxicology Testing Market, By Geography, 2013
Figure 25 Key Growth Stratagies, 2011–March 2014

★調査レポート[世界の生体外毒性/毒性テスト市場動向及び予測(~2018)] ( In-Vitro Toxicology/ Toxicity Testing Market by Industry (Diagnostic, Pharmaceutical, Cosmetics, Chemical), Technology (Cell Culture, HTS, Omics), Applications (Systemic, Dermal, Ocular), Method (Cellular Assay, Ex vivo, In Silico) - Global Forecast to 2018 / BT 2373) 販売に関する免責事項
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