In Vivo Toxicology Market by Product (Instruments, Consumables (Animal models, Reagents & Kits)), Testing type (Chronic, Sub-chronic), Toxicity Endpoints (Immunotoxicity, Systemic, DART), Testing Facility (Outsourced, In-house) - Global Forecast to 2022

体内 (in vivo) 毒性の世界市場予測(~2022年):商品別(器機、消耗品(動物モデル、試薬と道具))、テストタイプ別(慢性、亜慢性)、毒性評価項目別(免疫毒性、全身毒性、発生・生殖毒性)、テスト施設別(外部委託、社内)

◆タイトル:In Vivo Toxicology Market by Product (Instruments, Consumables (Animal models, Reagents & Kits)), Testing type (Chronic, Sub-chronic), Toxicity Endpoints (Immunotoxicity, Systemic, DART), Testing Facility (Outsourced, In-house) - Global Forecast to 2022
◆商品コード:MAM-BT-6000
◆調査・発行会社:MarketsandMarkets
◆発行日:2018年2月14日
◆ページ数:198
◆レポート形式:PDF / 英語
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◆調査対象地域:グローバル
◆産業分野:バイオ技術
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【レポートの概要】

MarketsandMarketsが発行した当調査レポートでは、体内 (in vivo) 毒性の世界市場について調査・分析し、エグゼクティブサマリー、市場インサイト、市場概観/市場動向、市場シェア分析、種類別分析、セグメント別分析、地域別分析、体内 (in vivo) 毒性の世界市場規模及び予測、市場動向、競争状況、関連企業分析などの情報をお届けいたします。
・イントロダクション
・調査手法
・エグゼクティブサマリー
・プレミアムインサイト
・市場概要
・体内 (in vivo) 毒性市場:商品別
・体内 (in vivo) 毒性市場:テストタイプ別
・体内 (in vivo) 毒性市場:毒性評価項目別
・体内 (in vivo) 毒性市場:テスト施設別
・体内 (in vivo) 毒性市場:地域別
・競争状況
・企業プロファイル
・付録

“The global in vivo toxicology market is projected to grow at a CAGR of 6.9%.”
The in vivo toxicology market is expected to reach USD 6.14 billion by 2022 from an estimated USD 4.40 billion in 2017, at a CAGR of 6.9%. The key factors driving the growth of this market include, increasing pharmaceutical R&D activities, mandatory government regulations for animal testing, innovations in animal models, and the development of exclusive in vivo toxicology tests. On the other hand, alternative methods to animal testing and disadvantages associated with animal toxicology testing likely to restrain the growth of this market.

“The instruments segment is expected to grow at the highest CAGR during the forecast period”
On the basis of product, the in vivo toxicology market is segmented into consumables and instruments. The consumables segment is further divided into reagents & kits and animal models. The instruments segment is expected to grow at the highest rate during the forecast period. The growth of this segment can be attributed to the increasing research on biological samples (such as blood and urine) using bioanalytical equipment.

“Chronic toxicity testing holds the largest share in the global in vivo toxicology market by testing type”
Based on testing type, the global in vivo toxicology market is segmented into acute, sub-acute, sub-chronic, and chronic toxicity testing. In 2017, chronic toxicity testing segment is estimated to hold the largest share in the global in vivo toxicology market. The large share of this market is attributed to the high cost of in vivo testing for more than 90 days, maintaining the animals, quality of tests, and the long duration of the tests performed.

“The immunotoxicity segment is expected to grow at the highest CAGR during the forecast period.”
On the basis of toxicity endpoint, the global in vivo toxicology market is segmented into immunotoxicity, systemic toxicity, carcinogenicity, genotoxicity, developmental and reproductive toxicity (DART), and other toxicity endpoints (includes organ toxicity, endocrine disruptor toxicity, juvenile toxicity, phototoxicity, ocular toxicity, and skin irritation). In 2017, the immunotoxicity segment is expected to account for the largest share in the in vivo toxicology market, this segment is also expected to grow at the highest CAGR during the forecast period. Rising demand for the development of biologics for autoimmune diseases and cancer and the increasing growth of biosimilars in oncology are driving the growth of this segment.

“China to witness the highest growth in the APAC region during the forecast period (2017-2022)”
In the APAC region, China is expected to witness the highest growth during the study period. The rising R&D funding and collaborations; initiatives taken by the Chinese government to promote life science research; and the strong trend of commercialization of biotechnology research are contributing to the growth of in vivo toxicology market in China.

Break of primary participants was as mentioned below:
• By Company Type – Tier 1–29%, Tier 2–35% and Tier 3–36%
• By Designation – C-level–39%, Director Level–35%, Others–26%
• By Region – North America–42%, Europe–36%, Asia Pacific–13%, RoW–9%

The major players in the global in vivo toxicology market are Thermo Fisher (US), Danaher (US), Charles River (US), Covance (LabCorp), and The Jackson Laboratory (US).
Research Coverage:
The report analyzes the in vivo toxicology market and aims at estimating the market size and future growth potential of this market based on various aspects such as products, testing type, toxicity endpoint, testing facility and region. The report also includes the competitive analysis of the key players in this market along with their company profiles, product offerings, recent developments, and key market strategies.
Reasons to Buy the Report
The report will help established firms as well as new entrants/smaller firms to gauge the pulse of the market, which in-turn would help them, garner a greater share of the market. Firms purchasing the report could use one or a combination of the below-mentioned strategies to strengthen their position in the market.
This report provides insights on the following pointers:
• Market Penetration: Comprehensive information on product portfolios offered by key players in the global in vivo toxicology market. The report analyzes the global in vivo toxicology market by product, testing type, toxicity endpoint, testing facility, and region
• Product and Service Innovation: Detailed insights on upcoming trends and product and service launches in the global in vivo toxicology market
• Market Development: Comprehensive information about the lucrative emerging markets by product, testing type, toxicity endpoint, testing facility, and region
• Market Diversification: Exhaustive information about new products, growing geographies, recent developments, and investments in the global in vivo toxicology market
• Competitive Assessment: In-depth assessment of market shares and growth strategies of leading players in the global market

【レポートの目次】

TABLE OF CONTENTS

1 INTRODUCTION 15
1.1 OBJECTIVES OF THE STUDY 15
1.2 DEFINITION 15
1.3 MARKET SCOPE 16
1.3.1 MARKETS COVERED 16
1.4 YEARS CONSIDERED FOR THE STUDY 16
1.5 CURRENCY 17
1.6 LIMITATIONS 17
1.7 STAKEHOLDERS 17
2 RESEARCH METHODOLOGY 18
2.1 RESEARCH DATA 18
2.2 MARKET RANKING 20
2.2.1 SECONDARY DATA 20
2.2.1.1 Secondary sources 20
2.2.2 PRIMARY DATA 21
2.2.2.1 Key data from Primary sources 21
2.2.2.2 Key industry insights 22
2.3 MARKET SIZE ESTIMATION 23
2.3.1 BOTTOM-UP APPROACH 23
2.3.2 TOP-DOWN APPROACH 24
2.4 MARKET BREAKDOWN AND DATA TRIANGULATION 25
2.5 ASSUMPTIONS 26
3 EXECUTIVE SUMMARY 27
4 PREMIUM INSIGHTS 31
4.1 ATTRACTIVE OPPORTUNITIES IN THE IN VIVO TOXICOLOGY MARKET 31
4.2 IN VIVO TOXICOLOGY MARKET, BY TESTING TYPE 31
4.3 EUROPE: IN VIVO TOXICOLOGY MARKET, BY TOXICITY ENDPOINT AND BY COUNTRY/REGION 32
4.4 IN VIVO TOXICOLOGY MARKET: DEVELOPING VS. DEVELOPED COUNTRIES 32
4.5 GLOBAL IN VIVO TOXICOLOGY MARKET: GEOGRAPHIC SNAPSHOT 33
5 MARKET OVERVIEW 34
5.1 INTRODUCTION 34
5.2 MARKET DYNAMICS 34
5.2.1 DRIVERS 35
5.2.1.1 Increasing pharmaceutical R&D activities 35
5.2.1.2 Mandatory government regulations for animal testing 36
5.2.1.3 Innovations in animal models 36
5.2.1.4 Exclusive in vivo toxicology tests 37
5.2.2 RESTRAINTS 38
5.2.2.1 Alternative methods to animal testing 38
5.2.2.2 Disadvantages associated with animal toxicology testing 38
5.2.3 OPPORTUNITIES 39
5.2.3.1 Increasing research in oncology and personalized medicine 39
5.2.3.2 Rising demand for humanized animal models 39
5.2.4 CHALLENGES 40
5.2.4.1 Regulations and laws for the ethical use of animals in research 40
6 IN VIVO TOXICOLOGY MARKET, BY PRODUCT 41
6.1 INTRODUCTION 42
6.2 CONSUMABLES 43
6.2.1 REAGENTS & KITS 44
6.2.2 ANIMAL MODELS 45
6.2.2.1 Mice models 46
6.2.2.2 Rat models 48
6.2.2.3 Other animal models 49
6.3 INSTRUMENTS 51
7 IN VIVO TOXICOLOGY MARKET, BY TESTING TYPE 53
7.1 INTRODUCTION 54
7.2 CHRONIC TOXICITY TESTING 55
7.3 SUB-CHRONIC TOXICITY TESTING 56
7.4 SUB-ACUTE TOXICITY TESTING 57
7.5 ACUTE TOXICITY TESTING 58
8 IN VIVO TOXICOLOGY MARKET, BY TOXICITY ENDPOINT 60
8.1 INTRODUCTION 61
8.2 IMMUNOTOXICITY 62
8.3 SYSTEMIC TOXICITY 63
8.4 CARCINOGENICITY 64
8.5 GENOTOXICITY 66
8.6 DEVELOPMENTAL AND REPRODUCTIVE TOXICITY (DART) 67
8.7 OTHER TOXICITY ENDPOINTS 68

9 IN VIVO TOXICOLOGY MARKET, BY TESTING FACILITY 70
9.1 INTRODUCTION 71
9.2 OUTSOURCED TESTING FACILITIES 72
9.3 IN-HOUSE TESTING FACILITIES 74
10 IN VIVO TOXICOLOGY MARKET, BY REGION 76
10.1 INTRODUCTION 77
10.2 NORTH AMERICA 78
10.2.1 US 82
10.2.2 CANADA 87
10.3 EUROPE 90
10.3.1 GERMANY 95
10.3.2 UK 98
10.3.3 FRANCE 102
10.3.4 REST OF EUROPE (ROE) 105
10.4 ASIA PACIFIC 110
10.4.1 JAPAN 114
10.4.2 CHINA 118
10.4.3 INDIA 122
10.4.4 REST OF ASIA PACIFIC 126
10.5 LATIN AMERICA 130
10.6 MIDDLE EAST & AFRICA 134
11 COMPETITIVE LANDSCAPE 138
11.1 OVERVIEW 138
11.2 RANKING OF PLAYERS 139
11.3 MARKET SHARE ANALYSIS 140
11.4 COMPETITIVE SCENARIO 142
11.4.1 PRODUCT & SERVICE LAUNCHES 142
11.4.2 COLLABORATIONS, PARTNERSHIPS, AND AGREEMENTS 142
11.4.3 ACQUISITIONS AND MERGERS 143
11.4.4 EXPANSIONS 143
11.4.5 OTHER DEVELOPMENTS 144

12 COMPANY PROFILES 145
(Business Overview, Products Offered, Recent Developments, SWOT Analysis, Mnm View)*
12.1 THERMO FISHER SCIENTIFIC 145
12.2 DANAHER 150
12.3 CHARLES RIVER LABORATORIES 155
12.4 LABCORP 159
12.5 THE JACKSON LABORATORY 163
12.6 DATA SCIENCES INTERNATIONAL 167
12.7 ENVIGO 169
12.8 EUROFINS SCIENTIFIC 172
12.9 PERKINELMER 176
12.10 SRI INTERNATIONAL 179
12.11 TACONIC BIOSCIENCES 182
12.12 WUXI APPTEC 184
*Business Overview, Products Offered, Recent Developments, SWOT Analysis, Mnm View might not be captured in case of unlisted companies.
13 APPENDIX 187
13.1 INSIGHTS OF INDUSTRY EXPERTS 187
13.2 DISCUSSION GUIDE 188
13.3 KNOWLEDGE STORE: MARKETSANDMARKETS’ SUBSCRIPTION PORTAL 191
13.4 INTRODUCING RT: REAL-TIME MARKET INTELLIGENCE 193
13.5 RELATED REPORTS 195
13.6 AUTHOR DETAILS 196

LIST OF TABLES

TABLE 1 INNOVATIVE ANIMAL MODELS DEVELOPED AND LAUNCHED BY PLAYERS 37
TABLE 2 REGULATORY AUTHORITIES OVERSEEING THE USE OF ANIMAL MODELS IN RESEARCH 40
TABLE 3 IN VIVO TOXICOLOGY MARKET, BY PRODUCT, 2015–2022 (USD MILLION) 42
TABLE 4 IN VIVO TOXICOLOGY CONSUMABLES MARKET, BY SEGMENT,
2015–2022 (USD MILLION) 43
TABLE 5 IN VIVO TOXICOLOGY CONSUMABLES MARKET, BY COUNTRY,
2015–2022 (USD MILLION) 43
TABLE 6 REAGENTS & KITS MARKET, BY COUNTRY, 2015–2022 (USD MILLION) 44
TABLE 7 ANIMAL MODELS MARKET, BY TYPE, 2015–2022 (USD MILLION) 45
TABLE 8 ANIMAL MODELS MARKET, BY COUNTRY, 2015–2022 (USD MILLION) 46
TABLE 9 MICE MODELS MARKET, BY COUNTRY, 2015–2022 (USD MILLION) 47
TABLE 10 RAT MODELS MARKET, BY COUNTRY, 2015–2022 (USD MILLION) 48
TABLE 11 OTHER ANIMAL MODELS MARKET, BY COUNTRY, 2015–2022 (USD MILLION) 50
TABLE 12 IN VIVO TOXICOLOGY INSTRUMENTS MARKET, BY COUNTRY,
2015–2022 (USD MILLION) 52
TABLE 13 IN VIVO TOXICOLOGY MARKET, BY TYPE, 2015–2022 (USD MILLION) 55
TABLE 14 CHRONIC TOXICITY TESTING MARKET, BY COUNTRY, 2015–2022 (USD MILLION) 56
TABLE 15 SUB-CHRONIC TOXICITY TESTING MARKET, BY COUNTRY,
2015–2022 (USD MILLION) 57
TABLE 16 SUB-ACUTE TOXICITY TESTING MARKET, BY COUNTRY, 2015–2022 (USD MILLION) 58
TABLE 17 ACUTE TOXICITY TESTING MARKET, BY COUNTRY, 2015–2022 (USD MILLION) 59
TABLE 18 IN VIVO TOXICOLOGY MARKET, BY TOXICITY ENDPOINT, 2015–2022 (USD MILLION) 62
TABLE 19 IN VIVO TOXICOLOGY MARKET FOR IMMUNOTOXICITY, BY COUNTRY,
2015–2022 (USD MILLION) 63
TABLE 20 IN VIVO TOXICOLOGY MARKET FOR SYSTEMIC TOXICITY, BY COUNTRY,
2015–2022 (USD MILLION) 64
TABLE 21 IN VIVO TOXICOLOGY MARKET FOR CARCINOGENICITY, BY COUNTRY,
2015–2022 (USD MILLION) 65
TABLE 22 IN VIVO TOXICOLOGY MARKET FOR GENOTOXICITY, BY COUNTRY,
2015–2022 (USD MILLION) 67
TABLE 23 IN VIVO TOXICOLOGY MARKET FOR DEVELOPMENTAL AND REPRODUCTIVE TOXICITY, BY COUNTRY, 2015–2022 (USD MILLION) 68
TABLE 24 IN VIVO TOXICOLOGY MARKET FOR OTHER TOXICITY ENDPOINTS, BY COUNTRY, 2015–2022 (USD MILLION) 69
TABLE 25 IN VIVO TOXICOLOGY MARKET, BY TESTING FACILITY, 2015–2022 (USD MILLION) 72
TABLE 26 IN VIVO TOXICOLOGY MARKET FOR OUTSOURCED TESTING FACILITIES,
BY COUNTRY, 2015–2022 (USD MILLION) 73
TABLE 27 IN VIVO TOXICOLOGY MARKET FOR IN-HOUSE TESTING FACILITIES, BY COUNTRY, 2015–2022 (USD MILLION) 75
TABLE 28 IN VIVO TOXICOLOGY MARKET, BY COUNTRY/REGION, 2015–2022 (USD MILLION) 78
TABLE 29 NORTH AMERICA: IN VIVO TOXICOLOGY MARKET, BY COUNTRY,
2015–2022 (USD MILLION) 80
TABLE 30 NORTH AMERICA: IN VIVO TOXICOLOGY MARKET, BY PRODUCT,
2015–2022 (USD MILLION) 80
TABLE 31 NORTH AMERICA: IN VIVO TOXICOLOGY CONSUMABLES MARKET, BY SEGMENT, 2015–2022 (USD MILLION) 80
TABLE 32 NORTH AMERICA: IN VIVO TOXICOLOGY MARKET FOR ANIMAL MODELS, BY TYPE, 2015–2022 (USD MILLION) 81
TABLE 33 NORTH AMERICA: IN VIVO TOXICOLOGY MARKET, BY TESTING TYPE,
2015–2022 (USD MILLION) 81
TABLE 34 NORTH AMERICA: IN VIVO TOXICOLOGY MARKET, BY TOXICITY ENDPOINT,
2015–2022 (USD MILLION) 82
TABLE 35 NORTH AMERICA: IN VIVO TOXICOLOGY MARKET, BY TESTING FACILITY,
2015–2022 (USD MILLION) 82
TABLE 36 NIH FUNDING FOR PROJECTS RELATED TO ANIMAL MODELS 83
TABLE 37 US: IN VIVO TOXICOLOGY MARKET, BY PRODUCT, 2015–2022 (USD MILLION) 84
TABLE 38 US: IN VIVO TOXICOLOGY CONSUMABLES MARKET, BY SEGMENT,
2015–2022 (USD MILLION) 85
TABLE 39 US: IN VIVO TOXICOLOGY MARKET FOR ANIMAL MODELS, BY TYPE,
2015–2022 (USD MILLION) 85
TABLE 40 US: IN VIVO TOXICOLOGY MARKET, BY TESTING TYPE, 2015–2022 (USD MILLION) 86
TABLE 41 US: IN VIVO TOXICOLOGY MARKET, BY TOXICITY ENDPOINT,
2015–2022 (USD MILLION) 86
TABLE 42 US: IN VIVO TOXICOLOGY MARKET, BY TESTING FACILITY,
2015–2022 (USD MILLION) 87
TABLE 43 CANADA: IN VIVO TOXICOLOGY MARKET, BY PRODUCT, 2015–2022 (USD MILLION) 88
TABLE 44 CANADA: IN VIVO TOXICOLOGY CONSUMABLES MARKET, BY SEGMENT,
2015–2022 (USD MILLION) 88
TABLE 45 CANADA: IN VIVO TOXICOLOGY MARKET FOR ANIMAL MODELS, BY TYPE,
2015–2022 (USD MILLION) 89
TABLE 46 CANADA: IN VIVO TOXICOLOGY MARKET, BY TESTING TYPE,
2015–2022 (USD MILLION) 89
TABLE 47 CANADA: IN VIVO TOXICOLOGY MARKET, BY TOXICITY ENDPOINT,
2015–2022 (USD MILLION) 90
TABLE 48 CANADA: IN VIVO TOXICOLOGY MARKET, BY TESTING FACILITY,
2015–2022 (USD MILLION) 90
TABLE 49 EUROPE: IN VIVO TOXICOLOGY MARKET, BY COUNTRY, 2015–2022 (USD MILLION) 92
TABLE 50 EUROPE: IN VIVO TOXICOLOGY MARKET, BY PRODUCT, 2015–2022 (USD MILLION) 92
TABLE 51 EUROPE: IN VIVO TOXICOLOGY CONSUMABLES MARKET, BY SEGMENT,
2015–2022 (USD MILLION) 92
TABLE 52 EUROPE: IN VIVO TOXICOLOGY MARKET FOR ANIMAL MODELS, BY TYPE,
2015–2022 (USD MILLION) 93
TABLE 53 EUROPE: IN VIVO TOXICOLOGY MARKET, BY TESTING TYPE,
2015–2022 (USD MILLION) 93
TABLE 54 EUROPE: IN VIVO TOXICOLOGY MARKET, BY TOXICITY ENDPOINT,
2015–2022 (USD MILLION) 94
TABLE 55 EUROPE: IN VIVO TOXICOLOGY MARKET, BY TESTING FACILITY,
2015–2022 (USD MILLION) 94
TABLE 56 GERMANY: IN VIVO TOXICOLOGY MARKET, BY PRODUCT,
2015–2022 (USD MILLION) 96
TABLE 57 GERMANY: IN VIVO TOXICOLOGY CONSUMABLES MARKET, BY SEGMENT,
2015–2022 (USD MILLION) 96
TABLE 58 GERMANY: IN VIVO TOXICOLOGY MARKET FOR ANIMAL MODELS, BY TYPE,
2015–2022 (USD MILLION) 96
TABLE 59 GERMANY: IN VIVO TOXICOLOGY MARKET, BY TESTING TYPE,
2015–2022 (USD MILLION) 97
TABLE 60 GERMANY: IN VIVO TOXICOLOGY MARKET, BY TOXICITY ENDPOINT,
2015–2022 (USD MILLION) 97
TABLE 61 GERMANY: IN VIVO TOXICOLOGY MARKET, BY TESTING FACILITY,
2015–2022 (USD MILLION) 98
TABLE 62 UK: IN VIVO TOXICOLOGY MARKET, BY PRODUCT, 2015–2022 (USD MILLION) 99
TABLE 63 UK: IN VIVO TOXICOLOGY CONSUMABLES MARKET, BY SEGMENT,
2015–2022 (USD MILLION) 100
TABLE 64 UK: IN VIVO TOXICOLOGY MARKET FOR ANIMAL MODELS, BY TYPE,
2015–2022 (USD MILLION) 100
TABLE 65 UK: IN VIVO TOXICOLOGY MARKET, BY TESTING TYPE, 2015–2022 (USD MILLION) 101
TABLE 66 UK: IN VIVO TOXICOLOGY MARKET, BY TOXICITY ENDPOINT,
2015–2022 (USD MILLION) 101
TABLE 67 UK: IN VIVO TOXICOLOGY MARKET, BY TESTING FACILITY,
2015–2022 (USD MILLION) 102
TABLE 68 FRANCE: IN VIVO TOXICOLOGY MARKET, BY PRODUCT, 2015–2022 (USD MILLION) 103
TABLE 69 FRANCE: IN VIVO TOXICOLOGY CONSUMABLES MARKET, BY SEGMENT,
2015–2022 (USD MILLION) 103
TABLE 70 FRANCE: IN VIVO TOXICOLOGY MARKET FOR ANIMAL MODELS, BY TYPE,
2015–2022 (USD MILLION) 103
TABLE 71 FRANCE: IN VIVO TOXICOLOGY MARKET, BY TESTING TYPE,
2015–2022 (USD MILLION) 104
TABLE 72 FRANCE: IN VIVO TOXICOLOGY MARKET, BY TOXICITY ENDPOINT,
2015–2022 (USD MILLION) 104
TABLE 73 FRANCE: IN VIVO TOXICOLOGY MARKET, BY TESTING FACILITY,
2015–2022 (USD MILLION) 105
TABLE 74 ROE: IN VIVO TOXICOLOGY MARKET, BY PRODUCT, 2015–2022 (USD MILLION) 108
TABLE 75 ROE: IN VIVO TOXICOLOGY CONSUMABLES MARKET, BY SEGMENT,
2015–2022 (USD MILLION) 108
TABLE 76 ROE: IN VIVO TOXICOLOGY MARKET FOR ANIMAL MODELS, BY TYPE,
2015–2022 (USD MILLION) 108
TABLE 77 ROE: IN VIVO TOXICOLOGY MARKET, BY TESTING TYPE, 2015–2022 (USD MILLION) 109
TABLE 78 ROE: IN VIVO TOXICOLOGY MARKET, BY TOXICITY ENDPOINT,
2015–2022 (USD MILLION) 109
TABLE 79 ROE: IN VIVO TOXICOLOGY MARKET, BY TESTING FACILITY,
2015–2022 (USD MILLION) 110
TABLE 80 APAC: IN VIVO TOXICOLOGY MARKET, BY COUNTRY/REGION,
2015–2022 (USD MILLION) 112
TABLE 81 APAC: IN VIVO TOXICOLOGY MARKET, BY PRODUCT, 2015–2022 (USD MILLION) 112
TABLE 82 APAC: IN VIVO TOXICOLOGY CONSUMABLES MARKET, BY SEGMENT,
2015–2022 (USD MILLION) 112
TABLE 83 APAC: IN VIVO TOXICOLOGY MARKET FOR ANIMAL MODELS, BY TYPE,
2015–2022 (USD MILLION) 113
TABLE 84 APAC: IN VIVO TOXICOLOGY MARKET, BY TESTING TYPE,
2015–2022 (USD MILLION) 113
TABLE 85 APAC: IN VIVO TOXICOLOGY MARKET, BY TOXICITY ENDPOINT,
2015–2022 (USD MILLION) 114
TABLE 86 APAC: IN VIVO TOXICOLOGY MARKET, BY TESTING FACILITY,
2015–2022 (USD MILLION) 114
TABLE 87 RESEARCH COLLABORATIONS BY FOREIGN-AFFILIATED COMPANIES AND JAPANESE UNIVERSITIES/RESEARCH INSTITUTES (2016) 115
TABLE 88 JAPAN: IN VIVO TOXICOLOGY MARKET, BY PRODUCT, 2015–2022 (USD MILLION) 116
TABLE 89 JAPAN: IN VIVO TOXICOLOGY CONSUMABLES MARKET, BY SEGMENT,
2015–2022 (USD MILLION) 116
TABLE 90 JAPAN: IN VIVO TOXICOLOGY MARKET FOR ANIMAL MODELS, BY TYPE,
2015–2022 (USD MILLION) 117
TABLE 91 JAPAN: IN VIVO TOXICOLOGY MARKET, BY TESTING TYPE,
2015–2022 (USD MILLION) 117
TABLE 92 JAPAN: IN VIVO TOXICOLOGY MARKET, BY TOXICITY ENDPOINT,
2015–2022 (USD MILLION) 118
TABLE 93 JAPAN: IN VIVO TOXICOLOGY MARKET, BY TESTING FACILITY,
2015–2022 (USD MILLION) 118
TABLE 94 CHINA: IN VIVO TOXICOLOGY MARKET, BY PRODUCT, 2015–2022 (USD MILLION) 119
TABLE 95 CHINA: IN VIVO TOXICOLOGY CONSUMABLES MARKET, BY SEGMENT,
2015–2022 (USD MILLION) 120
TABLE 96 CHINA: IN VIVO TOXICOLOGY MARKET FOR ANIMAL MODELS, BY TYPE,
2015–2022 (USD MILLION) 120
TABLE 97 CHINA: IN VIVO TOXICOLOGY MARKET, BY TESTING TYPE,
2015–2022 (USD MILLION) 121
TABLE 98 CHINA: IN VIVO TOXICOLOGY MARKET, BY TOXICITY ENDPOINT,
2015–2022 (USD MILLION) 121
TABLE 99 CHINA: IN VIVO TOXICOLOGY MARKET, BY TESTING FACILITY,
2015–2022 (USD MILLION) 122
TABLE 100 INDIA: IN VIVO TOXICOLOGY MARKET, BY PRODUCT, 2015–2022 (USD MILLION) 124
TABLE 101 INDIA: IN VIVO TOXICOLOGY CONSUMABLES MARKET, BY SEGMENT,
2015–2022 (USD MILLION) 124
TABLE 102 INDIA: IN VIVO TOXICOLOGY MARKET FOR ANIMAL MODELS, BY TYPE,
2015–2022 (USD MILLION) 124
TABLE 103 INDIA: IN VIVO TOXICOLOGY MARKET, BY TESTING TYPE,
2015–2022 (USD MILLION) 125
TABLE 104 INDIA: IN VIVO TOXICOLOGY MARKET, BY TOXICITY ENDPOINT,
2015–2022 (USD MILLION) 125
TABLE 105 INDIA: IN VIVO TOXICOLOGY MARKET, BY TESTING FACILITY,
2015–2022 (USD MILLION) 126
TABLE 106 ROAPAC: IN VIVO TOXICOLOGY MARKET, BY PRODUCT, 2015–2022 (USD MILLION) 127
TABLE 107 ROAPAC: IN VIVO TOXICOLOGY CONSUMABLES MARKET, BY SEGMENT,
2015–2022 (USD MILLION) 128
TABLE 108 ROAPAC: IN VIVO TOXICOLOGY MARKET FOR ANIMAL MODELS, BY TYPE,
2015–2022 (USD MILLION) 128
TABLE 109 ROAPAC: IN VIVO TOXICOLOGY MARKET, BY TESTING TYPE,
2015–2022 (USD MILLION) 128
TABLE 110 ROAPAC: IN VIVO TOXICOLOGY MARKET, BY TOXICITY ENDPOINT,
2015–2022 (USD MILLION) 129
TABLE 111 ROAPAC: IN VIVO TOXICOLOGY MARKET, BY TESTING FACILITY,
2015–2022 (USD MILLION) 129
TABLE 112 LATIN AMERICA: IN VIVO TOXICOLOGY MARKET, BY PRODUCT,
2015–2022 (USD MILLION) 132
TABLE 113 LATIN AMERICA: IN VIVO TOXICOLOGY CONSUMABLES MARKET, BY SEGMENT, 2015–2022 (USD MILLION) 132
TABLE 114 LATIN AMERICA: IN VIVO TOXICOLOGY MARKET FOR ANIMAL MODELS, BY TYPE, 2015–2022 (USD MILLION) 132
TABLE 115 LATIN AMERICA: IN VIVO TOXICOLOGY MARKET, BY TESTING TYPE,
2015–2022 (USD MILLION) 133
TABLE 116 LATIN AMERICA: IN VIVO TOXICOLOGY MARKET, BY TOXICITY ENDPOINT,
2015–2022 (USD MILLION) 133
TABLE 117 LATIN AMERICA: IN VIVO TOXICOLOGY MARKET, BY TESTING FACILITY,
2015–2022 (USD MILLION) 134
TABLE 118 MIDDLE EAST & AFRICA: IN VIVO TOXICOLOGY MARKET, BY PRODUCT,
2015–2022 (USD MILLION) 135
TABLE 119 MIDDLE EAST & AFRICA: IN VIVO TOXICOLOGY CONSUMABLES MARKET, BY SEGMENT, 2015–2022 (USD MILLION) 135
TABLE 120 MIDDLE EAST & AFRICA: IN VIVO TOXICOLOGY MARKET FOR ANIMAL MODELS,
BY TYPE, 2015–2022 (USD MILLION) 135
TABLE 121 MIDDLE EAST & AFRICA: IN VIVO TOXICOLOGY MARKET, BY TESTING TYPE,
2015–2022 (USD MILLION) 136
TABLE 122 MIDDLE EAST & AFRICA: IN VIVO TOXICOLOGY MARKET, BY TOXICITY ENDPOINT, 2015–2022 (USD MILLION) 136
TABLE 123 MIDDLE EAST & AFRICA: IN VIVO TOXICOLOGY MARKET, BY TESTING FACILITY, 2015–2022 (USD MILLION) 137
TABLE 124 RANK OF COMPANIES IN THE IN VIVO TOXICOLOGY MARKET,
BY INSTRUMENTS, 2017 139


LIST OF FIGURES

FIGURE 1 RESEARCH DESIGN 18
FIGURE 2 BREAKDOWN OF PRIMARY INTERVIEWS: BY COMPANY SIZE, DESIGNATION,
AND REGION 22
FIGURE 3 MARKET DATA TRIANGULATION METHODOLOGY 25
FIGURE 4 IN VIVO TOXICOLOGY MARKET, BY PRODUCT, 2017 VS. 2022 (USD BILLION) 27
FIGURE 5 IN VIVO TOXICOLOGY MARKET, BY TESTING TYPE, 2017 VS. 2022 (USD BILLION) 28
FIGURE 6 IN VIVO TOXICOLOGY MARKET, BY TOXICITY ENDPOINT,
2017 VS. 2022 (USD BILLION) 28
FIGURE 7 IN VIVO TOXICOLOGY MARKET, BY TESTING FACILITY,
2017 VS. 2022 (USD BILLION) 29
FIGURE 8 GEOGRAPHICAL SNAPSHOT OF THE IN VIVO TOXICOLOGY MARKET 30
FIGURE 9 INCREASING PHARMACEUTICAL R&D ACTIVITIES AND MANDATORY GOVERNMENT REGULATIONS FOR ANIMAL TESTING TO DRIVE MARKET GROWTH 31
FIGURE 10 CHRONIC TESTING SEGMENT TO COMMAND THE LARGEST SHARE IN THE
MARKET IN 2017 31
FIGURE 11 IMMUNOTOXICITY SEGMENT TO COMMAND THE LARGEST SHARE IN THE EUROPEAN MARKET IN 2017 32
FIGURE 12 DEVELOPING COUNTRIES TO GROW AT THE HIGHEST RATE FROM 2017 TO 2022 32
FIGURE 13 CHINA TO REGISTER HIGHEST GROWTH DURING THE FORECAST PERIOD 33
FIGURE 14 IN VIVO TOXICOLOGY MARKET: DRIVERS, RESTRAINTS, OPPORTUNITIES, AND CHALLENGES 34
FIGURE 15 PHARMACEUTICAL R&D EXPENDITURE IN THE US, EUROPE, AND JAPAN
(2000—2015) 35
FIGURE 16 CONSUMABLES SEGMENT WILL CONTINUE TO DOMINATE THE IN VIVO TOXICOLOGY MARKET DURING THE FORECAST PERIOD 42
FIGURE 17 CHRONIC TOXICITY TESTING SEGMENT WILL CONTINUE TO DOMINATE THE IN VIVO TOXICOLOGY MARKET IN 2022 54
FIGURE 18 IMMUNOTOXICITY SEGMENT WILL CONTINUE TO DOMINATE THE IN VIVO TOXICOLOGY MARKET IN 2022 61
FIGURE 19 OUTSOURCED TESTING FACILITIES WILL CONTINUE TO DOMINATE THE IN VIVO TOXICOLOGY MARKET IN 2022 71
FIGURE 20 IN VIVO TOXICOLOGY MARKET: GEOGRAPHIC GROWTH OPPORTUNITIES 77
FIGURE 21 NORTH AMERICA: IN VIVO TOXICOLOGY MARKET SNAPSHOT 79
FIGURE 22 EUROPE: IN VIVO TOXICOLOGY MARKET SNAPSHOT 91
FIGURE 23 NUMBER OF CELL THERAPY PRECLINICAL STUDIES IN THE UK (2013–2016) 99
FIGURE 24 ROE COUNTRIES: PHARMACEUTICAL INDUSTRY R&D EXPENDITURE (2015) 105
FIGURE 25 APAC: IN VIVO TOXICOLOGY MARKET SNAPSHOT 111
FIGURE 26 INDIA: R&D SPENDING BY TOP PHARMA GIANTS IN FY 2016 123
FIGURE 27 LATAM: IN VIVO TOXICOLOGY MARKET SNAPSHOT 131
FIGURE 28 COMPANIES ADOPTED PRODUCT & SERVICE LAUNCHES AS THEIR KEY GROWTH STRATEGY OVER THE LAST THREE YEARS 138
FIGURE 29 GLOBAL ANIMAL MODELS MARKET SHARE, BY KEY PLAYER, 2016 140
FIGURE 30 GLOBAL IN VIVO TOXICOLOGY SERVICES (CRO) MARKET SHARE,
BY KEY PLAYER, 2016 141
FIGURE 31 THERMO FISHER SCIENTIFIC: COMPANY SNAPSHOT 145
FIGURE 32 DANAHER: COMPANY SNAPSHOT 150
FIGURE 33 CHARLES RIVER LABORATORIES: COMPANY SNAPSHOT 155
FIGURE 34 LABCORP: COMPANY SNAPSHOT 159
FIGURE 35 THE JACKSON LABORATORY: COMPANY SNAPSHOT 163
FIGURE 36 ENVIGO: COMPANY SNAPSHOT 169
FIGURE 37 EUROFINS SCIENTIFIC: COMPANY SNAPSHOT 172
FIGURE 38 PERKINELMER: COMPANY SNAPSHOT 176


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